Walking performance is better in those with multiple sclerosis (MS), who have both higher levels of physical activity and peak oxygen consumption (VO2peak).
Higher VO2peak alone was not seen to improve walking outcomes; moderate-to-vigorous physical activity (MVPA) alone may improve walking outcomes.
Why this matters
In those living with MS, a chronic inflammatory disease, a decline is seen in both physical activity and VO2peak over time. These are thought to contribute to poorer walking performance.
Any strategies to improve this declining walking performance are eagerly sought by the 2.3 million people living with MS globally.