Plasma total tau as a biomarker of basal forebrain atrophy

Takeaway

  • Increased plasma concentrations of baseline total tau were significantly associated with basal forebrain atrophy in people at risk of Alzheimer’s disease (AD).

Why this matters

    Less invasive blood-based biomarkers for AD are crucial for early diagnosis; this study shows that plasma total tau was associated with atrophy in the basal forebrain.