Discovering a novel locus associated with white matter hyperintensity volume in non-demented elders

Takeaway

  • A genome-wide association study identified a significant association between rs7220676 near HS3ST3A1 and MIR548H3 genes which was associated with white matter hyperintensity volume (WMHV) in non-demented adults.

Why this matters

    Identification of a novel locus associated with WMHV and cognitive decline may help to further understand the underlying mechanisms of cognitive disorders.