BMI and vitamin D are independent causal risk factors for multiple sclerosis

Takeaway

  • Increased BMI and low vitamin D are causal risk factors for multiple sclerosis (MS)

Why this matters

  • While epidemiological studies have shown an association between environmental risk factors for MS, they can be subject to confounding and reverse causation.

  • The findings suggest that addressing these risk factors in early life among high-risk individuals could be beneficial.